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Formula Atlas

Infant formulas with 2′-FL HMO

2′-Fucosyllactose (2′-FL) is the most abundant human milk oligosaccharide and the first commercially produced HMO analog. It appears in most premium US formulas (Similac 360, Enfamil NeuroPro/Enspire, Gerber Good Start) and an expanding set of private-label and European products.

27 formulas matching · back to all formulas

What this list includes, and what it leaves out

Included
Formulas recorded as containing 2'-FL HMO, the most abundant human milk oligosaccharide and the one with the most trial data.
Left out
Formulas whose only prebiotic is GOS or FOS. Those are structurally related but not the same molecule, and they feed a broader set of bacteria rather than the HMO specialists.
Price per ounce across the 27 formulas on this list, cheapest first.

Typical US retail price, normalised to USD per ounce of powder. Imported European formulas carry shipping and importer margin; US retail brands are typically cheapest per ounce. Subscribe-and-save and private-label pricing can shift the ranking. 2 ready-to-feed products are left out: liquid is priced per fluid ounce, which is not comparable to a price per ounce of powder.

Data table
FormulaPrice per ounce
Kirkland Signature ProCare$0.88
Up&Up Sensitive$0.92
Parent's Choice Advantage Premium$0.96
Mama Bear Advantage$1.00
Up&Up Advantage Premium$1.04
Gerber Good Start GentlePro$1.13
Similac Sensitive$1.46
Similac Pro-Advance$1.51
Gerber Nature's Select Organic$1.59
Enfamil Sensitive$1.80
Similac Pro-Total Comfort$1.86
Aptamil Profutura Stage 1 (German)$1.88
ByHeart Whole Nutrition$1.88
Enfamil NeuroPro$1.88
Gerber Good Start SoothePro$1.90
Similac 360 Total Care$1.91
Similac 360 Total Care Sensitive$1.96
Enfamil NeuroPro Gentlease$2.00
Enfamil Enspire$2.02
Nannycare Stage 1$2.34
Nannycare Stage 2$2.34
Kabrita Stage 1$2.71
Gerber Extensive HA$3.19
Kabrita Stage 2$3.21
Similac Alimentum$3.97

Related reading

All matching formulas

Atlas last verified 2026-08-18. This site provides research and comparisons, not medical advice. Consult your pediatrician before changing your baby's formula.