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Similac Pro-Total Comfort, Similac
Similac

Similac Pro-Total Comfort

Stage 1 · US · hydrolyzed-whey

  • FDA Infant Formula Registration
  • Corn syrup solids
  • Soy

Verified · María López Botín

At a glance

Brand
Similac
Stage
1 (0–12 months)
Origin
US
Protein source
hydrolyzed-whey
Primary carbohydrate
corn-syrup-solids
DHA / ARA (per 100 ml)
11 mg / , mg
Certifications
FDA Infant Formula Registration
Price (USD / tin)
$38.99(verified 2026-04-20)

Cost calculator

What does Similac Similac Pro-Total Comfort actually cost?

Slide to your baby's age. Numbers reflect AAP-typical consumption with peak at 3–6 months and tapering after solid foods at 6 months.

03691215+

Daily intake

30 oz

Monthly cost

$258

Year-1 remaining

$1966

9 months

Compared at age 3mo

  • Similac Similac Pro-Total Comfort$258/mo
  • Nutramigen Nutramigen Ready-to-Feed$57/mo$-201
  • Premibio Premibio Premilait Stage 1$161/mo$-97
  • Neocate Neocate Syneo Infant$737/mo+$479
Volume averages from AAP feeding guidance. Individual intake varies; budget projections are estimates, not prescriptions. Pricing as last verified on the SKU page.
Where Similac Pro-Total Comfort sits among 12 hypoallergenic formulas in the Atlas.

Compared against every other hypoallergenic powder formula tracked in the Atlas. Position is not a verdict: more DHA is not automatically better, and a lower price is not automatically worse.

Data table
MetricThis formulaMedianRange
DHA (mg/100 ml)11.011.011.014.0
Protein (g/100 ml)1.501.691.352.10
Iron (mg/100 ml)1.201.200.501.20
Price (USD/oz)1.862.630.875.32

Fat blend composition

Palm oil supplies palmitic acid (~25% of breast-milk fatty acids). Whole-milk fat preserves natural sn-2 palmitate and MFGM; sn-2 palmitate (structured palm) addresses the position issue; standard palm + supplementary oils is the conventional EU-organic approach. See the palm oil explainer for the hierarchy.

  • Palm oil presentNo
  • Soy oil or lecithinYes

Red flags (per label)

  • Corn syrup solidsYes
  • MaltodextrinNo
  • CarrageenanNo
  • Synthetic beta-caroteneNo
  • GMO-derivedNo

Differentiators

  • Partially hydrolyzed whey (pHF)
  • 2'-FL HMO included
  • Reduced-lactose composition
  • Abbott's Similac partial hydrolysate, direct competitor to Enfamil Gentlease and Gerber GentlePro
  • Similac's entry in the US partial hydrolysate category, competes with Enfamil Gentlease in the 'gentle on fussiness and gas' commercial positioning

Ingredients (resolved)

  • corn-syrup-solids
  • hydrolyzed-whey
  • vegetable-oil-blend
  • safflower-oil
  • soybean-oil
  • coconut-oil
  • mortierella-alpina-oil
  • fish-oil
  • calcium-phosphate
  • potassium-chloride
  • calcium-carbonate
  • potassium-citrate
  • sodium-citrate
  • magnesium-chloride
  • choline
  • taurine
  • l-carnitine
  • iron-sulfate
  • zinc-sulfate
  • vitamin-c
  • inositol
  • niacin
  • pantothenic-acid
  • copper-sulfate
  • manganese-sulfate
  • vitamin-e
  • vitamin-a
  • thiamin
  • vitamin-b2-riboflavin
  • vitamin-b6
  • folic-acid
  • potassium-iodide
  • biotin
  • vitamin-k1
  • sodium-selenite
  • vitamin-d3
  • vitamin-b12

Similac Pro-Total Comfort compared against

This site provides research and comparisons, not medical advice. Consult your pediatrician before changing your baby's formula.