Similac Pro-Advance
Stage 1 · US · skimmed-cow-milk
- FDA Infant Formula Registration
- Soy
Verified · María López Botín
At a glance
- Brand
- Similac
- Stage
- 1 (0–12 months)
- Origin
- US
- Protein source
- skimmed-cow-milk
- Primary carbohydrate
- lactose
- DHA / ARA (per 100 ml)
- 11.3 mg / 22.6 mg
- Certifications
- FDA Infant Formula Registration
- Price (USD / tin)
- $35.00(verified 2026-04-19)
Cost calculator
What does Similac Similac Pro-Advance actually cost?
Slide to your baby's age. Numbers reflect AAP-typical consumption with peak at 3–6 months and tapering after solid foods at 6 months.
Daily intake
30 oz
Monthly cost
$209
Year-1 remaining
$1596
9 months
Compared at age 3mo
- Similac Similac Pro-Advance$209/mo
- Nutramigen Nutramigen Ready-to-Feed$57/mo$-152
- Premibio Premibio Premilait Stage 1$161/mo$-48
- Neocate Neocate Syneo Infant$737/mo+$528
Compared against every other standard powder formula tracked in the Atlas. Position is not a verdict: more DHA is not automatically better, and a lower price is not automatically worse.
Data table
| Metric | This formula | Median | Range |
|---|---|---|---|
| DHA (mg/100 ml) | 11.3 | 14.0 | 8.0–20.0 |
| Protein (g/100 ml) | 1.33 | 1.40 | 1.25–2.50 |
| Iron (mg/100 ml) | 1.20 | 1.00 | 0.50–2.00 |
| Price (USD/oz) | 1.51 | 1.64 | 0.88–3.21 |
Fat blend composition
Palm oil supplies palmitic acid (~25% of breast-milk fatty acids). Whole-milk fat preserves natural sn-2 palmitate and MFGM; sn-2 palmitate (structured palm) addresses the position issue; standard palm + supplementary oils is the conventional EU-organic approach. See the palm oil explainer for the hierarchy.
- Palm oil presentNo
- Soy oil or lecithinYes
Red flags (per label)
- Corn syrup solidsNo
- MaltodextrinNo
- CarrageenanNo
- Synthetic beta-caroteneYes
- GMO-derivedNo
Differentiators
- 2'-FL HMO (first US mass-market to include)
- Lactose-first composition (unlike Pro-Sensitive)
- FDA-registered
- Palm-oil-free in this specific Pro-Advance formulation
- Original Similac line with 2'-FL HMO, the HMO-fortified US formula most covered by WIC
Ingredients (resolved)
- skimmed-cow-milk
- lactose
- safflower-oil
- whey-protein-concentrate
- soybean-oil
- coconut-oil
- gos
- schizochytrium-oil
- mortierella-alpina-oil
- beta-carotene-synthetic
- soy-lecithin
- l-tryptophan
- taurine
- inositol
- nucleotides
- calcium-carbonate
- potassium-citrate
- potassium-hydroxide
- magnesium-chloride
- sodium-chloride
- iron-sulfate
- calcium-phosphate
- zinc-sulfate
- copper-sulfate
- manganese-sulfate
- potassium-iodide
- sodium-selenite
- vitamin-c
- choline
- vitamin-e
- niacin
- pantothenic-acid
- vitamin-a
- thiamin
- vitamin-b2-riboflavin
- vitamin-b6
- folic-acid
- vitamin-k1
- vitamin-d3
- biotin
- vitamin-b12
Similac Pro-Advance compared against
- Holle Cow Stage 1 vs Similac Pro-Advance - Demeter Biodynamic vs US 2'-FL HMO
- Jovie Goat Stage 1 vs Similac Pro-Advance - EU Organic Goat-Milk vs US 2'-FL HMO Cow-Milk
- Kabrita Stage 1 vs Similac Pro-Advance - Dutch Goat-Milk with sn-2 Palmitate vs US Cow-Milk Mainstream
- Kendamil Classic Stage 1 vs Similac Pro-Advance - Two Routes to a Palm-Free Formula
- Lebenswert Stage 1 vs Similac Pro-Advance - Bioland Minimalist EU Organic vs US 2'-FL HMO
- Loulouka Stage 1 vs Similac Pro-Advance - Swiss EU Organic No-Palm No-Soy vs US 2'-FL HMO Mainstream
This site provides research and comparisons, not medical advice. Consult your pediatrician before changing your baby's formula.